A “just in case” test that proved its value about 3 years later
I took Mantara’s saliva-based pharmacogenomics (PGx) test a few years ago and filed the report away. It turned out to be far more useful than I expected. Amongst other things, it showed I’m a fast metaboliser of common stomach-protection medicines (PPIs such as lansoprazole/omeprazole).
About three years later, when my GP prescribed an anti-inflammatory painkiller, they also added lansoprazole because I’m on rivaroxaban (a blood thinner) and that combination can increase the risk of a serious stomach bleed. Because I had the PGx report, we could take into account that standard lanzoprazole doses may be less effective for me — it indicated I may need up to 4× the usual dose for the same protection. My GP adjusted the dose, which may well have helped me avoid a gastric bleed and what can follow: many days in hospital, urgent investigations, possible transfusions, and in worse cases emergency procedures/surgery — plus weeks out of action. As someone who is self-employed, that would have been a major personal and financial hit (as well as a cost to the NHS).
Taking the test is a simple process, with clear report, and it’s genuinely useful when you’re prescribed something new — it helps you have a more informed discussion with your GP. I’d recommend it even if you’re not currently on regular medication.

Reply from Mantara Health






